Hyperinsulinemia: A link between obesity and hypertension?
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چکیده
منابع مشابه
Hypoadiponectinemia: a novel link between obesity and hypertension?
Hypertension is a public health challenge of increasing importance because of its high frequency and concomitant risk of cardiovascular and renal disease. It has been estimated that the worldwide prevalence of hypertension was 972 million in 2000, and this number will increase by 60% by the year 2025.1 A large body of evidence indicates that the increasing prevalence of hypertension is sustaine...
متن کاملIs insulin the link between hypertension and obesity?
Oral glucose tolerance tests with plasma glucose and insulin determinations were performed on 195 patients with impaired glucose tolerance. Patients were divided into three groups according to blood pressure levels: normal, below 140/90 mm Hg; diastolic hypertension, diastolic pressure above 90 mm Hg; and systolic hypertension, systolic pressure above 140 and diastolic pressure below 90 mm Hg. ...
متن کاملInsulin Resistance , Hyperinsulinemia , and Obesity - Associated Hypertension 1
Recent work to elucidate the cause of obesity-associated hypertension has focused on insulin resistance and hyperinsulinemia. A significant amount of epidemiologic and correlational evidence suggests a link between these factors and obesity-associated hypertension, and acute insulin infusion studies have revealed renal, neural, and cardiovascular effects of this hormone that, if maintained chro...
متن کاملHyperinsulinemia: a Cause of Obesity?
PURPOSE OF REVIEW This perspective is motivated by the need to question dogma that does not work: that the problem is insulin resistance (IR). We highlight the need to investigate potential environmental obesogens and toxins. RECENT FINDINGS The prequel to severe metabolic disease includes three interacting components that are abnormal: (a) IR, (b) elevated lipids and (c) elevated basal insul...
متن کاملThe relationship between hyperinsulinemia, hypertension and progressive renal disease.
The incidence of end-stage renal disease (ESRD) has risen dramatically in the past decade, mainly due to the increasing prevalence of diabetes mellitus, and both impaired glucose tolerance and hypertension are important contributors to rising rates of ESRD. Obesity, especially the visceral type, is associated with peripheral resistance to insulin actions and hyperinsulinemia, which predisposes ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1993
ISSN: 0085-2538
DOI: 10.1038/ki.1993.197